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Chemical structure of ALW-II-41-27

GC11134

ALW-II-41-27

Also known as N-[5-[[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]carbamoyl]-2-methylphenyl]-5-thiophen-2-ylpyridine-3-carboxamide

ALW-II-41-27 is an Eph family tyrosine kinase inhibitor with an IC50 of 11 nM to inhibit Eph2

ChemicalCAS1186206-79-0MW607.69FormulaC32H32F3N5O2S
CAS number
1186206-79-0
Molecular weight
607.69
Formula
C32H32F3N5O2S
Solubility
≥ 102 mg/mL in DMSO, ≥ 60·8 mg/mL in EtOH
InChIKey
HYWXBDQAYLPMIX-UHFFFAOYSA-N
Catalogue number
GC11134
Brand
GLPBIO
Computed properties PubChem CID 42628503 · XLogP 5.1 · TPSA 106 Ų · H-bond donors 2
XLogP
5.1
TPSA
106 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
8
Heavy atoms
43

SMILES CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)NC(=O)C4=CN=CC(=C4)C5=CC=CS5)C(F)(F)F

Computed descriptors from PubChem (CID 42628503), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.