Loading...
Chemical structure of Leptomycin B

GC10954

Leptomycin B

Also known as (2E,10E,12E,16E,18E)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-19-(3-methyl-6-oxo-2,3-dihydropyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid

Leptomycin B (LMB) is an inhibitor of chromosome region maintenance 1 (CRM1) that is one of the nuclear protein exporters

ChemicalCAS87081-35-4MW540.74FormulaC33H48O6
CAS number
87081-35-4
Molecular weight
540.74
Formula
C33H48O6
Solubility
50mg/mL in Methanol, 50 mg/ml in Ethanol
InChIKey
YACHGFWEQXFSBS-SAYXANOCSA-N
Catalogue number
GC10954
Brand
GLPBIO
Computed properties PubChem CID 5458861 · XLogP 7.9 · TPSA 101 Ų · H-bond donors 2
XLogP
7.9
TPSA
101 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
15
Heavy atoms
39

SMILES CC/C(=C\C(C)C/C=C/C(=C/C(C)C(=O)C(C)C(C(C)C/C(=C/C(=O)O)/C)O)/C)/C=C/C1C(C=CC(=O)O1)C

Computed descriptors from PubChem (CID 5458861), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.