Loading...
Chemical structure of XL335

GC10760

XL335

Also known as propan-2-yl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-2,6-dihydroazepino[4,5-b]indole-5-carboxylate

XL335 (FXR-450) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM

ChemicalCAS629664-81-9MW438.48FormulaC25H24F2N2O3
CAS number
629664-81-9
Molecular weight
438.48
Formula
C25H24F2N2O3
Solubility
≥ 20·4mg/mL in DMSO
InChIKey
INASOKQDNHHMRE-UHFFFAOYSA-N
Catalogue number
GC10760
Brand
GLPBIO
Computed properties PubChem CID 10026128 · XLogP 5.1 · TPSA 62.4 Ų · H-bond donors 1
XLogP
5.1
TPSA
62.4 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
32

SMILES CC(C)OC(=O)C1=CN(CC(C2=C1NC3=CC=CC=C32)(C)C)C(=O)C4=CC(=C(C=C4)F)F

Computed descriptors from PubChem (CID 10026128), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.