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Chemical structure of PF-4708671

GC10689

PF-4708671

Also known as 2-[[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-6-(trifluoromethyl)-1H-benzimidazole

PF-4708671, is a novel cell-permeable inhibitor of S6K1, specifically inhibits the S6K1 isoform with a Ki of 20 nM and IC50 of 160 nM

ChemicalCAS1255517-76-0MW390.41FormulaC19H21F3N6
CAS number
1255517-76-0
Molecular weight
390.41
Formula
C19H21F3N6
Solubility
≥ 19·5mg/mL in DMSO
InChIKey
FBLPQCAQRNSVHB-UHFFFAOYSA-N
Catalogue number
GC10689
Brand
GLPBIO
Computed properties PubChem CID 51371303 · XLogP 3.2 · TPSA 60.9 Ų · H-bond donors 1
XLogP
3.2
TPSA
60.9 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
4
Heavy atoms
28

SMILES CCC1=CN=CN=C1N2CCN(CC2)CC3=NC4=C(N3)C=C(C=C4)C(F)(F)F

Computed descriptors from PubChem (CID 51371303), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.