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Chemical structure of Plinabulin

GC10235

Plinabulin

Also listed as Plinabulin (NPI-2358)

Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agen (VDA) against tubulin-depolymerizing with an IC50 of 9·8 nM against HT-29 cells· Plinabulin (NPI-2358) binds the colchicine binding site of β-tubulin preventing polymerization and has potent inhibitory to tumor cells

ChemicalCAS714272-27-2MW336.39FormulaC19H20N4O2
CAS number
714272-27-2
Molecular weight
336.39
Formula
C19H20N4O2
Solubility
DMF： 20 mg/ml,DMSO： 20 mg/ml,DMSO：PBS (pH 7·2) (1：1)： 0·5 mg/ml,Ethanol： 1 mg/ml
InChIKey
UNRCMCRRFYFGFX-TYPNBTCFSA-N
Catalogue number
GC10235
Brand
GLPBIO
Computed properties PubChem CID 9949641 · XLogP 2.8 · TPSA 86.9 Ų · H-bond donors 3
XLogP
2.8
TPSA
86.9 Ų
H-bond donors
3
H-bond acceptors
3
Rotatable bonds
3
Heavy atoms
25

SMILES CC(C)(C)C1=C(N=CN1)/C=C\2/C(=O)N/C(=C\C3=CC=CC=C3)/C(=O)N2

Computed descriptors from PubChem (CID 9949641), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.