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Chemical structure of WS-383 (free base)

GB40411

WS-383 (free base)

Also listed as WS-383 - DCN1-UBC12 interaction inhibitor E31

WS-383 effectively blocks interaction between DCN1 and UBC12 (IC50 value of 11 nM), causes selective Cul3/1 neddylation inhibition over other cullins, and induces accumulation of p21, p27, and NRF2

ChemicalCAS2247543-65-1MW461.99FormulaC18H20ClN9S2
CAS number
2247543-65-1
Molecular weight
461.99
Formula
C18H20ClN9S2
InChIKey
MGESDQAAIJOGJA-UHFFFAOYSA-N
Catalogue number
GB40411
Brand
GLPBIO
Computed properties PubChem CID 138319704 · XLogP 3.8 · TPSA 141 Ų · H-bond donors 0
XLogP
3.8
TPSA
141 Ų
H-bond donors
0
H-bond acceptors
9
Rotatable bonds
8
Heavy atoms
30

SMILES CC1=NC2=NC(=NN2C(=C1)SC3=NN=NN3CCN(C)C)SCC4=CC=C(C=C4)Cl

Computed descriptors from PubChem (CID 138319704), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.