GB40373
Spindlactone B
Also listed as SPL-B - Spindlactone B
Orally active inhibitor of transforming acidic coiled-coil protein (TACC3) that selectively inhibits the nucleation of centrosome microtubules in ovarian cancer cells, without affecting spindle assembly in normal cells· SPL significantly inhibits mitosis in cancer cells and suppresses in vivo tumor growth
ChemicalCAS1465248-60-5MW454.47FormulaC27H22N2O5
- CAS number
- 1465248-60-5
- Molecular weight
- 454.47
- Formula
- C27H22N2O5
- InChIKey
- IGRGLGHQFJOWOD-UHFFFAOYSA-N
- Catalogue number
- GB40373
- Brand
- GLPBIO
Computed properties PubChem CID 72192437 · XLogP 3.4 · TPSA 89 Ų · H-bond donors 1
- XLogP
- 3.4
- TPSA
- 89 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Rotatable bonds
- 6
- Heavy atoms
- 34
SMILES CCN(CC1=CC=NC=C1)CC2=C(C=CC3=C2OC(=O)C=C3C4=CC5=CC=CC=C5OC4=O)O
Computed descriptors from PubChem (CID 72192437), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il