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Chemical structure of SP-6-27

GB40371

SP-6-27

Also known as 2-amino-7-(dimethylamino)-4-[4-(dimethylamino)naphthalen-1-yl]-4H-chromene-3-carbonitrile

The microtubule inhibitor SP-6-27 inhibits angiogenesis and induces apoptosis in ovarian cancer cells· Moreover, SP-6-27 is active against four human glioma cell lines (T98, U87, LN18, A172) and particularly against the A172 glioma cell line (IC50 value of 7·4 nM)

ChemicalCAS1384170-58-4MW384.47FormulaC24H24N4O
CAS number
1384170-58-4
Molecular weight
384.47
Formula
C24H24N4O
InChIKey
XWCSZMDVKNZVMD-UHFFFAOYSA-N
Catalogue number
GB40371
Brand
GLPBIO
Computed properties PubChem CID 53357723 · XLogP 4.8 · TPSA 65.5 Ų · H-bond donors 1
XLogP
4.8
TPSA
65.5 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
3
Heavy atoms
29

SMILES CN(C)C1=CC2=C(C=C1)C(C(=C(O2)N)C#N)C3=CC=C(C4=CC=CC=C34)N(C)C

Computed descriptors from PubChem (CID 53357723), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.