Loading...
Chemical structure of Nvp-bbd130

GB40303

Nvp-bbd130

Also listed as NVP-BBD130 - BBD 130

Orally potent and selective dual PI3K/mTOR inhibitor; IC50 values to be 72, 2336, 201 and 382 nM for PI3K p110 α, β, δ and γ isoforms, respectively; inhibition of PI3K/mTOR pathway like NVP-BEZ235, BBD130 efficiently attenuates growth and proliferation of melanoma primary tumors and metastasis

ChemicalCAS853910-61-9MW443.5FormulaC28H21N5O
CAS number
853910-61-9
Molecular weight
443.5
Formula
C28H21N5O
InChIKey
ISHNPDWTQUXPSY-UHFFFAOYSA-N
Catalogue number
GB40303
Brand
GLPBIO
Computed properties PubChem CID 11751126 · XLogP 4.3 · TPSA 73.1 Ų · H-bond donors 0
XLogP
4.3
TPSA
73.1 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
34

SMILES CC(C)(C#N)C1=CC=C(C=C1)N2C3=C4C=C(C=CC4=NC=C3N(C2=O)C)C#CC5=CN=CC=C5

Computed descriptors from PubChem (CID 11751126), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.