Loading...
Chemical structure of iGP-1

GB40239

iGP-1

Also known as 4-[4-(1H-benzimidazol-2-yl)anilino]-4-oxobutanoic acid

iGP-1 (27031-00-1) is a potent and cell permeable inhibitor of mitochondrial glycerol-3-phosphate dehydrogenase (mGPDH), IC50=6·3 μM, that is selective over the cytosolic enzyme· It does not block pyruvate uptake into cells or mitochondria and has no direct effect on glycolysis in synaptosomes· This novel inhibitor is a unique tool which may be used to investigate the role of glycerol-3-phosphate metabolism in isolated and intact systems

ChemicalCAS27031-00-1MW309.32FormulaC17H15N3O3
CAS number
27031-00-1
Molecular weight
309.32
Formula
C17H15N3O3
InChIKey
ARVPDCQNTCJVSU-UHFFFAOYSA-N
Catalogue number
GB40239
Brand
GLPBIO
Computed properties PubChem CID 767937 · XLogP 1.8 · TPSA 95.1 Ų · H-bond donors 3
XLogP
1.8
TPSA
95.1 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
5
Heavy atoms
23

SMILES C1=CC=C2C(=C1)NC(=N2)C3=CC=C(C=C3)NC(=O)CCC(=O)O

Computed descriptors from PubChem (CID 767937), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.