GB40120
BFF 122 - BF 5
Also known as (2S)-6-(4-aminopiperazin-1-yl)-7-fluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
Potent and selective inhibitor of kynurenine aminotransferase II (IC50 values ca· 1 μM and >30 μM for KAT II and KAT I respectively)· Intrastriatal BFF 122 decreased newly formed KYNA by 66%, without influencing 3-HK or QUIN production in naÏve rats
ChemicalCAS1152314-49-2MW362.36FormulaC17H19FN4O4
- CAS number
- 1152314-49-2
- Molecular weight
- 362.36
- Formula
- C17H19FN4O4
- InChIKey
- ICQVSZFWVUBYSI-VIFPVBQESA-N
- Catalogue number
- GB40120
- Brand
- GLPBIO
Computed properties PubChem CID 46829291 · XLogP -1.1 · TPSA 99.3 Ų · H-bond donors 2
- XLogP
- -1.1
- TPSA
- 99.3 Ų
- H-bond donors
- 2
- H-bond acceptors
- 9
- Rotatable bonds
- 2
- Heavy atoms
- 26
SMILES C[C@H]1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)N)F)C(=O)O
Computed descriptors from PubChem (CID 46829291), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il