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Chemical structure of BF844

GB40119

BF844

Also known as 1-(4-chloro-3,5-diphenylpyrazolo[3,4-c]pyridazin-1-yl)-2-methylpropan-2-ol

BF844 is a stabilizer of CLRN1N48K in vitro and in vivo· BF844 effectively attenuated progressive hearing loss and prevented deafness in an Usher syndrome type III (USH3) mouse model

ChemicalCAS1404506-35-9MW378.85FormulaC21H19ClN4O
CAS number
1404506-35-9
Molecular weight
378.85
Formula
C21H19ClN4O
InChIKey
TVNSCKMVODVWRS-UHFFFAOYSA-N
Catalogue number
GB40119
Brand
GLPBIO
Computed properties PubChem CID 66576257 · XLogP 3.6 · TPSA 63.8 Ų · H-bond donors 1
XLogP
3.6
TPSA
63.8 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
27

SMILES CC(C)(CN1C2=NN=C(C(=C2C(=N1)C3=CC=CC=C3)Cl)C4=CC=CC=C4)O

Computed descriptors from PubChem (CID 66576257), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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