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Chemical structure of ABT 102

GB40088

ABT 102

Also known as 1-[(1R)-5-tert-butyl-2,3-dihydro-1H-inden-1-yl]-3-(1H-indazol-4-yl)urea

Potent and selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptors (IC50 values to be 5-7 nM) under clinical trials; TRVP1 receptor antagonism is a promising approach for pain management

ChemicalCAS808756-71-0MW348.44FormulaC21H24N4O
CAS number
808756-71-0
Molecular weight
348.44
Formula
C21H24N4O
InChIKey
TYOYXJNGINZFET-GOSISDBHSA-N
Catalogue number
GB40088
Brand
GLPBIO
Computed properties PubChem CID 11256560 · XLogP 4.2 · TPSA 69.8 Ų · H-bond donors 3
XLogP
4.2
TPSA
69.8 Ų
H-bond donors
3
H-bond acceptors
2
Rotatable bonds
3
Heavy atoms
26

SMILES CC(C)(C)C1=CC2=C(C=C1)[C@@H](CC2)NC(=O)NC3=CC=CC4=C3C=NN4

Computed descriptors from PubChem (CID 11256560), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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