Loading...
Chemical structure of 5-HT6 antagonist 29

GB40076

5-HT6 antagonist 29

Also known as 3-(4-chlorophenyl)sulfonyl-1-methyl-7-piperazin-1-ylindole;hydrochloride

Selective brain penetrant 5-HT6 receptor antagonist (pKi value 8·6)· Close regio-isomer of SB 699929 with brain-blood ratio of 2·6:1 and ED50 value of 5 mg/kg (po), and thus twice as potent as SB 271046

ChemicalCAS497963-70-9MW426.36FormulaC19H20ClN3O2S·HCl
CAS number
497963-70-9
Molecular weight
426.36
Formula
C19H20ClN3O2S·HCl
InChIKey
MERMVFOBIFLWLA-UHFFFAOYSA-N
Catalogue number
GB40076
Brand
GLPBIO
Computed properties PubChem CID 91826472 · TPSA 62.7 Ų · H-bond donors 2 · H-bond acceptors 4
TPSA
62.7 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
27

SMILES CN1C=C(C2=C1C(=CC=C2)N3CCNCC3)S(=O)(=O)C4=CC=C(C=C4)Cl.Cl

Computed descriptors from PubChem (CID 91826472), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.