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Chemical structure of 5-HT3 antagonist 5

GC65983

5-HT3 antagonist 5

Also known as N-(4-methoxyphenyl)quinoxaline-2-carboxamide

5-HT3 antagonist 5 is a quinoxalin-2-carboxamide compound, a 5-HT3 receptor antagonist· 5-HT3 antagonist 5 exerts antagonism on 5-HT3 agonist and 2-methyl-5-HT, and shows anti-depressant effect in mice

ChemicalCAS901599-43-7MW279.29FormulaC16H13N3O2
CAS number
901599-43-7
Molecular weight
279.29
Formula
C16H13N3O2
Solubility
DMSO : 20·83 mg/mL (74·58 mM; ultrasonic and warming and heat to 60°C)
InChIKey
UUFCEPQEIQOEAL-UHFFFAOYSA-N
Catalogue number
GC65983
Brand
GLPBIO
Computed properties PubChem CID 4416580 · XLogP 2.9 · TPSA 64.1 Ų · H-bond donors 1
XLogP
2.9
TPSA
64.1 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
21

SMILES COC1=CC=C(C=C1)NC(=O)C2=NC3=CC=CC=C3N=C2

Computed descriptors from PubChem (CID 4416580), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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