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Chemical structure of Z-Val-Ala-DL-Asp(OMe)-fluoromethylketone

GA23962

Z-Val-Ala-DL-Asp(OMe)-fluoromethylketone

Also known as methyl 5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-4-oxopentanoate

Z-VAD(OMe)-FMK, a pan-caspase inhibitor, is a competitive irreversible peptide inhibitor and blocks caspase-1 family and caspase-3 family enzymes· The methyl ester of Z-VAD-FMK has been used in studies to support the hypothesis that inhibitors of caspases can limit brain infarction resulting from the permanent obstruction of a brain artery

ChemicalCAS634911-81-2MW467.5FormulaC22H30FN3O7
CAS number
634911-81-2
Molecular weight
467.5
Formula
C22H30FN3O7
Solubility
Soluble in DMSO
InChIKey
MIFGOLAMNLSLGH-SXUUOERCSA-N
Catalogue number
GA23962
Brand
GLPBIO
Computed properties PubChem CID 5497173 · XLogP 1.9 · TPSA 140 Ų · H-bond donors 3
XLogP
1.9
TPSA
140 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
14
Heavy atoms
33

SMILES C[C@@H](C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)[C@H](C(C)C)NC(=O)OCC1=CC=CC=C1

Computed descriptors from PubChem (CID 5497173), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.