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Chemical structure of Z-Gly-Pro-Phe-Pro-Leu-OH

GA23824

Z-Gly-Pro-Phe-Pro-Leu-OH

Also known as (2S)-4-methyl-2-[[(2S)-1-[(2S)-3-phenyl-2-[[(2S)-1-[2-(phenylmethoxycarbonylamino)acetyl]pyrrolidine-2-carbonyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]pentanoic acid

GPFPL, a sequence inhibiting serine proteinases, and its derivative Z-GPFPL have been used in skin care products as the pentapeptide inhibits desquamation of human skin

ChemicalCAS61867-13-8MW663.77FormulaC35H45N5O8
CAS number
61867-13-8
Molecular weight
663.77
Formula
C35H45N5O8
Solubility
Soluble in DMSO
InChIKey
CKNVGZIRPDUFOZ-DZUOILHNSA-N
Catalogue number
GA23824
Brand
GLPBIO
Computed properties PubChem CID 67128077 · XLogP 3.5 · TPSA 174 Ų · H-bond donors 4
XLogP
3.5
TPSA
174 Ų
H-bond donors
4
H-bond acceptors
8
Rotatable bonds
15
Heavy atoms
48

SMILES CC(C)C[C@@H](C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H]3CCCN3C(=O)CNC(=O)OCC4=CC=CC=C4

Computed descriptors from PubChem (CID 67128077), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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