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Chemical structure of Z-Gly-Pro-Leu-Gly-Pro-OH

GA23822

Z-Gly-Pro-Leu-Gly-Pro-OH

Also known as (2S)-1-[2-[[(2S)-4-methyl-2-[[(2S)-1-[2-(phenylmethoxycarbonylamino)acetyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]acetyl]pyrrolidine-2-carboxylic acid

Substrate for collagenase and for prolyl endopeptidase (post-proline cleaving enzyme)· Cleavage of Z-GPLGP yields Z-Gly-Pro-OH (C-1880) and H-Leu-Gly-Pro-OH (H-3895), an antihypertensive peptide

ChemicalCAS2646-61-9MW573.65FormulaC28H39N5O8
CAS number
2646-61-9
Molecular weight
573.65
Formula
C28H39N5O8
Solubility
Soluble in DMSO
InChIKey
DGRDYZZPQWDRBB-FKBYEOEOSA-N
Catalogue number
GA23822
Brand
GLPBIO
Computed properties PubChem CID 193354 · XLogP 1.5 · TPSA 174 Ų · H-bond donors 4
XLogP
1.5
TPSA
174 Ų
H-bond donors
4
H-bond acceptors
8
Rotatable bonds
13
Heavy atoms
41

SMILES CC(C)C[C@@H](C(=O)NCC(=O)N1CCC[C@H]1C(=O)O)NC(=O)[C@@H]2CCCN2C(=O)CNC(=O)OCC3=CC=CC=C3

Computed descriptors from PubChem (CID 193354), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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