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Chemical structure of Z-Gly-Pro-AMC

GA23817

Z-Gly-Pro-AMC

Also known as benzyl N-[2-[(2S)-2-[(4-methyl-2-oxochromen-7-yl)carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]carbamate

Z-Gly-Pro-AMC functions as a fluorogenic substrate that is susceptible to hydrolysis by prolyl endopeptidase, resulting in the production of intensely fluorescent 7-amido-4-methylcoumarin· (Λex=380 nm, Λem=465 nm)

ChemicalCAS68542-93-8MW463.49FormulaC25H25N3O6
CAS number
68542-93-8
Molecular weight
463.49
Formula
C25H25N3O6
Solubility
DMSO ： 125 mg/mL (269·70 mM; Need ultrasonic)
InChIKey
YWOXKKRKNGWXEG-FQEVSTJZSA-N
Catalogue number
GA23817
Brand
GLPBIO
Computed properties PubChem CID 125702 · XLogP 2.3 · TPSA 114 Ų · H-bond donors 2
XLogP
2.3
TPSA
114 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
7
Heavy atoms
34

SMILES CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)[C@@H]3CCCN3C(=O)CNC(=O)OCC4=CC=CC=C4

Computed descriptors from PubChem (CID 125702), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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