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Chemical structure of H-Tyr-Ser-Pro-Trp-Thr-Asn-Phe-OH

GA22987

H-Tyr-Ser-Pro-Trp-Thr-Asn-Phe-OH

Also known as (2S)-2-[[(2S)-4-amino-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-hydroxybutanoyl]amino]-4-oxobutanoyl]amino]-3-phenylpropanoic acid

The heptapeptide YSPWTNF has been shown to prevent cellulitis in mice, which was induced by S· aureus strain Smith diffuse· Furthermore, RIP can also significantly reduce the overall pathology and delay the onset of disease symptoms in several other S· aureus infections, including keratitis, osteomyelitis, mastitis, and septic arthritis· These findings strongly evidence the potential value of RIP as a chemotherapeutic agent

ChemicalCAS228544-21-6MW913.99FormulaC45H55N9O12
CAS number
228544-21-6
Molecular weight
913.99
Formula
C45H55N9O12
Solubility
Soluble in DMSO
InChIKey
PMLYXWFMGMYGHQ-PIXADCCCSA-N
Catalogue number
GA22987
Brand
GLPBIO
Computed properties PubChem CID 9941067 · XLogP -3.2 · TPSA 349 Ų · H-bond donors 12
XLogP
-3.2
TPSA
349 Ų
H-bond donors
12
H-bond acceptors
13
Rotatable bonds
22
Heavy atoms
66

SMILES C[C@H]([C@@H](C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CO)NC(=O)[C@H](CC5=CC=C(C=C5)O)N)O

Computed descriptors from PubChem (CID 9941067), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
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