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Chemical structure of H-Tyr-Cys-Phe-Ala-Trp-Lys-Thr-Phe-Cys-OH

GA22966

H-Tyr-Cys-Phe-Ala-Trp-Lys-Thr-Phe-Cys-OH

Selective somatostatin receptor subtype sst4 agonist· In competitive radioligand displacement experiments using the non-selective radioligand ([¹²?I]-(Leu?,D-Trp²²,Tyr²?)-Somatostatin-28, YCFAWKTFC exhibited a high affinity for sst4 with an IC?? value of 2·0 ± 0·5 nM· IC?? values for sst1, sst2, sst3, and sst5 were >1000 nM, 622 ± 85 nM, 624 ± 213 nM, and 692 ± 166 nM, respectively· The nonapeptide YCFAWKTFC may serve as a lead compound or tool for preclinical and clinical studies

ChemicalCAS647016-22-6MW1166.39FormulaC57H71N11O12S2
CAS number
647016-22-6
Molecular weight
1166.39
Formula
C57H71N11O12S2
Solubility
Soluble in DMSO
Catalogue number
GA22966
Brand
GLPBIO

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