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Chemical structure of Cortistatin-17 (human)

GA21282

Cortistatin-17 (human)

Cortistatin-17 shows structural similarities to somatostatin· The peptide binds to all somatostatin receptor subtypes (SSTR) in a similar way as the rat cortistatin· Its inhibitory effects on forskolin-stimulated cAMP production in chinese hamster ovary cells expressing SSTR2-5 are dose dependent but slightly less efficient than that of somatostatin-14· Like the rat cortistatin it has an effect on sleep and wakefulness pattern in rat· It decreases the light slow wave sleep (SWS1) and increases the deep slow wave sleep (SWS2) in a dose dependent manner· Administration of the peptide causes a temporary flattening of cortical and hippocampal electroencephalograms

ChemicalCAS189450-19-9MW2151.53FormulaC96H139N27O24S3
CAS number
189450-19-9
Molecular weight
2151.53
Formula
C96H139N27O24S3
Solubility
Soluble in DMSO
Catalogue number
GA21282
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.