
GA21282
Cortistatin-17 (human)
Cortistatin-17 shows structural similarities to somatostatin· The peptide binds to all somatostatin receptor subtypes (SSTR) in a similar way as the rat cortistatin· Its inhibitory effects on forskolin-stimulated cAMP production in chinese hamster ovary cells expressing SSTR2-5 are dose dependent but slightly less efficient than that of somatostatin-14· Like the rat cortistatin it has an effect on sleep and wakefulness pattern in rat· It decreases the light slow wave sleep (SWS1) and increases the deep slow wave sleep (SWS2) in a dose dependent manner· Administration of the peptide causes a temporary flattening of cortical and hippocampal electroencephalograms
ChemicalCAS189450-19-9MW2151.53FormulaC96H139N27O24S3
- CAS number
- 189450-19-9
- Molecular weight
- 2151.53
- Formula
- C96H139N27O24S3
- Solubility
- Soluble in DMSO
- Catalogue number
- GA21282
- Brand
- GLPBIO
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il