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Chemical structure of Acetyl-Amyloid β-Protein (15-20) amide

GA20534

Acetyl-Amyloid β-Protein (15-20) amide

Also known as (2S)-2-acetamido-N-[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]pentanediamide

Incubation of Ac-QKLVFF-NH? with the amyloid β-protein (1-40) inhibited polymerization of the amyloid β-protein (1-40) into amyloid fibrils· The peptide is thought to block the polymerization sites

ChemicalCAS189064-06-0MW822.02FormulaC42H63N9O8
CAS number
189064-06-0
Molecular weight
822.02
Formula
C42H63N9O8
Solubility
Soluble in DMSO
InChIKey
DDXTVYDSGCHGAN-PITCCTKHSA-N
Catalogue number
GA20534
Brand
GLPBIO
Computed properties PubChem CID 71312114 · XLogP 1.8 · TPSA 287 Ų · H-bond donors 9
XLogP
1.8
TPSA
287 Ų
H-bond donors
9
H-bond acceptors
9
Rotatable bonds
26
Heavy atoms
59

SMILES CC(C)C[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)N)NC(=O)C

Computed descriptors from PubChem (CID 71312114), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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Lead time
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.