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Chemical structure of Ac-Arg-Gly-Lys(Ac)-AMC

GA20481

Ac-Arg-Gly-Lys(Ac)-AMC

Also known as (2S)-6-acetamido-2-[[2-[[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-N-(4-methyl-2-oxochromen-7-yl)hexanamide

Ac-RGK(Ac)-AMC, fluorogenic substrate for assaying histone deacetylase (HDAC) activity in a two-step enzymatic reaction· The assay consists of the initial lysine deacetylation by HDAC followed by the release of the fluorescent group by trypsin

ChemicalCAS660846-97-9MW600.68FormulaC28H40N8O7
CAS number
660846-97-9
Molecular weight
600.68
Formula
C28H40N8O7
Solubility
Soluble in DMSO
InChIKey
HABKINWCDDLXSZ-VXKWHMMOSA-N
Catalogue number
GA20481
Brand
GLPBIO
Computed properties PubChem CID 90475073 · XLogP -1.3 · TPSA 236 Ų · H-bond donors 7
XLogP
-1.3
TPSA
236 Ų
H-bond donors
7
H-bond acceptors
8
Rotatable bonds
16
Heavy atoms
43

SMILES CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)[C@H](CCCCNC(=O)C)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)C

Computed descriptors from PubChem (CID 90475073), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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