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Chemical structure of Caspase-8-IN-1

GA20471

Caspase-8-IN-1

Also listed as Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-aldehyde

Acetyl-AAVALLPAVLLALLAP-IETD-CHO, the potent reversible caspase-8 inhibitor IETD-CHO (N-1620) is rendered cell-permeable by attaching a non-polar CPP corresponding to the Kaposi fibroblast growth factor (FGF) signal peptide sequence

ChemicalCAS886462-83-5MW2000.42FormulaC95H162N20O26
CAS number
886462-83-5
Molecular weight
2000.42
Formula
C95H162N20O26
Solubility
Soluble in DMSO
InChIKey
JTCOYJXFAGGBGS-IVGKSQGSSA-N
Catalogue number
GA20471
Brand
GLPBIO
Computed properties PubChem CID 131862978 · XLogP 4.4 · TPSA 676 Ų · H-bond donors 21
XLogP
4.4
TPSA
676 Ų
H-bond donors
21
H-bond acceptors
26
Rotatable bonds
60
Heavy atoms
141

SMILES CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)C

Computed descriptors from PubChem (CID 131862978), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.