GA20375
1-Naphthalenylsulfonyl-Ile-Trp-aldehyde
Also known as (2S,3S)-N-[(2S)-1-(1H-indol-3-yl)-3-oxopropan-2-yl]-3-methyl-2-(naphthalen-1-ylsulfonylamino)pentanamide
Cell-permeable and reversible inhibitor of cathepsin L, a lysosomal cysteine protease ( IC?? 1·9 nM)· 1-Naphthalenylsulfonyl-IW-CHO inhibited the release of Ca²? and hydroxyproline from bone in an in vitro bone culture system· It should be useful for the treatment of osteoporosis
ChemicalCAS161709-56-4MW491.61FormulaC27H29N3O4S
- CAS number
- 161709-56-4
- Molecular weight
- 491.61
- Formula
- C27H29N3O4S
- Solubility
- Soluble in DMSO
- InChIKey
- FFPHAWVFZQFOJA-JCWFFFCVSA-N
- Catalogue number
- GA20375
- Brand
- GLPBIO
Computed properties PubChem CID 9957276 · XLogP 4.9 · TPSA 117 Ų · H-bond donors 3
- XLogP
- 4.9
- TPSA
- 117 Ų
- H-bond donors
- 3
- H-bond acceptors
- 5
- Rotatable bonds
- 10
- Heavy atoms
- 35
SMILES CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C=O)NS(=O)(=O)C3=CC=CC4=CC=CC=C43
Computed descriptors from PubChem (CID 9957276), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il