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Chemical structure of (D-Pro⁴,D-Trp⁷,⁹,¹⁰)-Substance P (4-11)

GA20154

(D-Pro⁴,D-Trp⁷,⁹,¹⁰)-Substance P (4-11)

Also known as (2S)-N-[(2S)-5-amino-1-[[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2R)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]-2-[[(2R)-pyrrolidine-2-carbonyl]amino]pentanediamide

A competitive antagonist at receptors for substance P, for bombesin and for cholecystokinin

ChemicalCAS86917-57-9MW1207.42FormulaC62H74N14O10S
CAS number
86917-57-9
Molecular weight
1207.42
Formula
C62H74N14O10S
Solubility
Soluble in DMSO
InChIKey
SFUBGXWEUDKBIR-XWYQIVALSA-N
Catalogue number
GA20154
Brand
GLPBIO
Computed properties PubChem CID 16131288 · XLogP 2.5 · TPSA 418 Ų · H-bond donors 14
XLogP
2.5
TPSA
418 Ų
H-bond donors
14
H-bond acceptors
12
Rotatable bonds
32
Heavy atoms
87

SMILES CSCC[C@@H](C(=O)N)NC(=O)[C@@H](CC1=CNC2=CC=CC=C21)NC(=O)[C@@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)[C@@H](CC6=CNC7=CC=CC=C76)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H]8CCCN8

Computed descriptors from PubChem (CID 16131288), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.