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Chemical structure of (7-Diethylaminocoumarin-3-yl)carbonyl-Amyloid β-Protein (1-40)

GA20024

(7-Diethylaminocoumarin-3-yl)carbonyl-Amyloid β-Protein (1-40)

Amyloid β-protein (1-40) that is N-terminally modified with the fluorescent dye (7-diethylaminocoumarin-3-yl)carbonyl (DAC or DEAC)· This derivative can be utilized to assess the binding properties of amyloid β-protein (1-40) for various membranes since it behaves very similar to the native peptide· In aqueous environments the fluorophore is almost non-fluorescent whereas binding to membranes results in an increase in fluorescence intensity (Λex = 430 nm, Λem = 470 nm)· Increases in the GM1 ganglioside and cholesterol content in the lipid bilayers facilitated the binding of this peptide· For phosphatidylcholine and phosphatidylserine no affinity was observed

ChemicalCAS1802087-66-6MW4573.13FormulaC208H308N54O61S
CAS number
1802087-66-6
Molecular weight
4573.13
Formula
C208H308N54O61S
Solubility
Soluble in DMSO
Catalogue number
GA20024
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.