AP73641
Recombinant Human Tumor necrosis factor receptor superfamily member 11B protein(TNFRSF11B) (Active)
Recombinant Human Tumor necrosis factor receptor superfamily member 11B protein(TNFRSF11B) (Active) (catalogue number AP73641) is a e.coli-derived recombinant protein. It targets Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B): Acts as a decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Supplied in 4 pack sizes, from 50ug at ₪1,370.52 to 1mg at ₪8,027.31; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- E.Coli
- UniProt ID
- O00300
- Gene
- TNFRSF11B
- Target organism
- Homo sapiens
- Catalogue number
- AP73641
- Brand
- LABO Scientific
- Storage
- The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Target background
Target: Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B) · Homo sapiens
Acts as a decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis
Subcellular location: Secreted
Tissue specificity: Highly expressed in adult lung, heart, kidney, liver, spleen, thymus, prostate, ovary, small intestine, thyroid, lymph node, trachea, adrenal gland, testis, and bone marrow. Detected at very low levels in brain, placenta and skeletal muscle. Highly expressed in fetal kidney, liver and lung
Sequence length: 401 aa · 46026 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il