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Recombinant Human Tumor necrosis factor receptor superfamily member 11B protein(TNFRSF11B) (Active)

AP73640

Recombinant Human Tumor necrosis factor receptor superfamily member 11B protein(TNFRSF11B) (Active)

Recombinant Human Tumor necrosis factor receptor superfamily member 11B protein(TNFRSF11B) (Active) (catalogue number AP73640) is a yeast-derived recombinant protein. It targets Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B): Acts as a decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Supplied in 4 pack sizes, from 50ug at ₪1,370.52 to 1mg at ₪8,027.31; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Recombinant ProteinHostYeast
Host / source
Yeast
UniProt ID
O00300
Gene
TNFRSF11B
Target organism
Homo sapiens
Catalogue number
AP73640
Brand
LABO Scientific
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Target background

Target: Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B) · Homo sapiens

Acts as a decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis

Subcellular location: Secreted

Tissue specificity: Highly expressed in adult lung, heart, kidney, liver, spleen, thymus, prostate, ovary, small intestine, thyroid, lymph node, trachea, adrenal gland, testis, and bone marrow. Detected at very low levels in brain, placenta and skeletal muscle. Highly expressed in fetal kidney, liver and lung

Sequence length: 401 aa · 46026 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.