
AP71925
Recombinant Human Endothelin-1(EDN1) (Active)
Recombinant Human Endothelin-1(EDN1) (Active) (catalogue number AP71925) is a e.coli-derived recombinant protein. It targets Endothelin-1 (EDN1): Endothelins are endothelium-derived vasoconstrictor peptides. Supplied as 1mg at ₪7,040.21; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- E.coli
- UniProt ID
- P05305
- Gene
- EDN1
- Target organism
- Homo sapiens
- Catalogue number
- AP71925
- Brand
- LABO Scientific
- Storage
- The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Target background
Target: Endothelin-1 (EDN1) · Homo sapiens
Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G protein-coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells. Also binds the DEAR/FBXW7-AS1 receptor. Promotes mesenteric arterial wall remodeling via activation of ROCK signaling and subsequent colocalization of NFATC3 with F-actin filaments. NFATC3 then translocates to the nucleus where it subsequently promotes the transcription of the smooth muscle hypertrophy and differentiation marker ACTA2
Subcellular location: Secreted
Tissue specificity: Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells
Sequence length: 212 aa · 24425 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il