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Recombinant Human Ubiquitin-conjugating Enzyme E2 R1

AP60440

Recombinant Human Ubiquitin-conjugating Enzyme E2 R1

Recombinant Human Ubiquitin-conjugating Enzyme E2 R1 (catalogue number AP60440) is a escherichia coli-derived recombinant protein. It targets Ubiquitin-conjugating enzyme E2 R1 (CDC34): E2 ubiquitin-conjugating enzyme that accepts ubiquitin from an E1 ubiquitin-activating protein, and catalyzes its covalent attachment to other proteins by an E3 ubiquitin-protein ligase complex. Supplied in 3 pack sizes, from 5ug at ₪444.60 to 500ug at ₪5,200.62; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Recombinant ProteinHostEscherichia coli
Host / source
Escherichia coli
UniProt ID
P49427
Gene
CDC34
Target organism
Homo sapiens
Catalogue number
AP60440
Brand
LABO Scientific
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 6 months from date of receipt, -20 to -70 ℃ as supplied.- 3 months, -20 to -70 ℃ under sterile conditions after opening.

Target background

Target: Ubiquitin-conjugating enzyme E2 R1 (CDC34) · Homo sapiens

E2 ubiquitin-conjugating enzyme that accepts ubiquitin from an E1 ubiquitin-activating protein, and catalyzes its covalent attachment to other proteins by an E3 ubiquitin-protein ligase complex. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Cooperates with the E2 UBCH5C and the SCF(FBXW11) E3 ligase complex for the polyubiquitination of NFKBIA leading to its subsequent proteasomal degradation. Performs ubiquitin chain elongation building ubiquitin chains from the UBE2D3-primed NFKBIA-linked ubiquitin.

Subcellular location: Cytoplasm; Nucleus

Tissue specificity: Expressed in testes during spermatogenesis to regulate repression of cAMP-induced transcription

Sequence length: 236 aa · 26737 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 6 months from date of receipt, -20 to -70 ℃ as supplied.- 3 months, -20 to -70 ℃ under sterile conditions after opening.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.