
AP60435
Recombinant Human Ubiquitin-conjugating Enzyme E2 D3, His
Recombinant Human Ubiquitin-conjugating Enzyme E2 D3, His (catalogue number AP60435) is a escherichia coli-derived recombinant protein. It targets Ubiquitin-conjugating enzyme E2 D3 (UBE2D3): Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Supplied in 3 pack sizes, from 10ug at ₪444.60 to 500ug at ₪4,662.20; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Escherichia coli
- UniProt ID
- P61077
- Gene
- UBE2D3
- Target organism
- Homo sapiens
- Catalogue number
- AP60435
- Brand
- LABO Scientific
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 6 months from date of receipt, -20 to -70 ℃ as supplied.- 3 months, -20 to -70 ℃ under sterile conditions after opening.
Target background
Target: Ubiquitin-conjugating enzyme E2 D3 (UBE2D3) · Homo sapiens
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'-linked polyubiquitination. Cooperates with the E2 CDC34 and the SCF(FBXW11) E3 ligase complex for the polyubiquitination of NFKBIA leading to its subsequent proteasomal degradation. Acts as an initiator E2, priming the phosphorylated NFKBIA target at positions 'Lys-21' and/or 'Lys-22' with a monoubiquitin. Ubiquitin chain elongation is then performed by CDC34, building ubiquitin chains from the UBE2D3-primed NFKBIA-linked ubiquitin.
Subcellular location: Cell membrane; Endosome membrane
Sequence length: 147 aa · 16687 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 6 months from date of receipt, -20 to -70 ℃ as supplied.- 3 months, -20 to -70 ℃ under sterile conditions after opening.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il