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Recombinant Rat Mesencephalic Astrocyte-Derived Neurotrophic Factor

AP60260

Recombinant Rat Mesencephalic Astrocyte-Derived Neurotrophic Factor

Recombinant Rat Mesencephalic Astrocyte-Derived Neurotrophic Factor (catalogue number AP60260) is a escherichia coli-derived recombinant protein. It targets Mesencephalic astrocyte-derived neurotrophic factor (Manf): Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Supplied in 3 pack sizes, from 5ug at ₪444.60 to 500ug at ₪13,786.73; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Recombinant ProteinHostEscherichia coli
Host / source
Escherichia coli
UniProt ID
P0C5H9
Gene
Manf
Target organism
Rattus norvegicus
Catalogue number
AP60260
Brand
LABO Scientific
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ℃ as supplied.- 1 month, 2 to 8 ℃ under sterile conditions after reconstitution.- 3 months, -20 to -70 ℃ under sterile conditions after reconstitution.

Target background

Target: Mesencephalic astrocyte-derived neurotrophic factor (Manf) · Rattus norvegicus

Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons. Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death. Retained in the ER/sarcoplasmic reticulum (SR) through association with the endoplasmic reticulum chaperone protein HSPA5 under normal conditions.

Subcellular location: Secreted; Endoplasmic reticulum lumen; Sarcoplasmic reticulum lumen

Tissue specificity: Expressed in plasma cells and macrophages in the splenic marginal zone (at protein level)

Sequence length: 179 aa · 20388 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ℃ as supplied.- 1 month, 2 to 8 ℃ under sterile conditions after reconstitution.- 3 months, -20 to -70 ℃ under sterile conditions after reconstitution.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.