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Recombinant Murine Mesencephalic Astrocyte-Derived Neurotrophic Factor

AP60206

Recombinant Murine Mesencephalic Astrocyte-Derived Neurotrophic Factor

Recombinant Murine Mesencephalic Astrocyte-Derived Neurotrophic Factor (catalogue number AP60206) is a escherichia coli-derived recombinant protein. It targets Mesencephalic astrocyte-derived neurotrophic factor (Manf): Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Supplied in 3 pack sizes, from 5ug at ₪444.60 to 500ug at ₪13,786.73; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Recombinant ProteinHostEscherichia coli
Host / source
Escherichia coli
UniProt ID
Q9CXI5
Gene
Manf
Target organism
Mus musculus
Catalogue number
AP60206
Brand
LABO Scientific
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ℃ as supplied.- 1 month, 2 to 8 ℃ under sterile conditions after reconstitution.- 3 months, -20 to -70 ℃ under sterile conditions after reconstitution.

Target background

Target: Mesencephalic astrocyte-derived neurotrophic factor (Manf) · Mus musculus

Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons. Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death. Retained in the ER/sarcoplasmic reticulum (SR) through association with the endoplasmic reticulum chaperone protein HSPA5 under normal conditions.

Subcellular location: Secreted; Endoplasmic reticulum lumen; Sarcoplasmic reticulum lumen

Tissue specificity: Strongly expressed in pancreatic islets and spermatocytes (at protein level). Expressed in chondrocytes in cartilage (at protein level). Expressed in prorepair macrophages in damaged skeletal muscles, expression decreases as animals age (at protein level)

Sequence length: 179 aa · 20388 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ℃ as supplied.- 1 month, 2 to 8 ℃ under sterile conditions after reconstitution.- 3 months, -20 to -70 ℃ under sterile conditions after reconstitution.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.