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ROCK2 Rabbit mAb

59513

ROCK2 Rabbit mAb

ROCK2 Rabbit mAb (catalogue number 59513) is a recombinant rabbit-derived kdko validated recombinant monoclonal antibody validated for WB ICC/IF, reactive with Human Mouse Rat samples. It targets Rho-associated protein kinase 2 (ROCK2): Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

KDKO Validated Recombinant Monoclonal AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Applications
WB ICC/IF
UniProt ID
O75116
Gene
ROCK2
Target organism
Homo sapiens
Catalogue number
59513
Brand
LABO Scientific
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

Target background

Target: Rho-associated protein kinase 2 (ROCK2) · Homo sapiens

Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p90RSK/RPS6KA1 during myogenic differentiation.

Subcellular location: Cytoplasm; Cell membrane; Nucleus; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome

Tissue specificity: Expressed in the brain (at protein level)

Sequence length: 1388 aa · 160900 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.