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14-3-3 sigma Rabbit mAb

59102

14-3-3 sigma Rabbit mAb

14-3-3 sigma Rabbit mAb (catalogue number 59102) is a recombinant rabbit-derived primary antibody validated for WB IHC, reactive with Human Rat samples. It targets 14-3-3 protein sigma (SFN): Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human Rat
Applications
WB IHC
UniProt ID
P31947
Gene
SFN
Target organism
Homo sapiens
Catalogue number
59102
Brand
LABO Scientific
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

Target background

Target: 14-3-3 protein sigma (SFN) · Homo sapiens

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Promotes cytosolic retention of GBP1 GTPase by binding to phosphorylated GBP1, thereby inhibiting the innate immune response. Also acts as a TP53/p53-regulated inhibitor of G2/M progression.

Subcellular location: Cytoplasm; Nucleus; Secreted

Tissue specificity: Present mainly in tissues enriched in stratified squamous keratinizing epithelium

Sequence length: 248 aa · 27774 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.