
49152
14-3-3 sigma Antibody
14-3-3 sigma Antibody (catalogue number 49152) is a rabbit-derived primary antibody validated for Western blot, Immunohistochemistry, reactive with Human, Rat samples. It targets 14-3-3 protein sigma (SFN): Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪2,035.38; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Rabbit
- Reactivity
- Human, Rat
- Applications
- Western blot Immunohistochemistry
- UniProt ID
- P31947
- Gene
- SFN
- Target organism
- Homo sapiens
- Catalogue number
- 49152
- Brand
- LABO Scientific
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Target background
Target: 14-3-3 protein sigma (SFN) · Homo sapiens
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Promotes cytosolic retention of GBP1 GTPase by binding to phosphorylated GBP1, thereby inhibiting the innate immune response. Also acts as a TP53/p53-regulated inhibitor of G2/M progression.
Subcellular location: Cytoplasm; Nucleus; Secreted
Tissue specificity: Present mainly in tissues enriched in stratified squamous keratinizing epithelium
Sequence length: 248 aa · 27774 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il