Loading...
Dnmt3a Rabbit mAb

58848

Dnmt3a Rabbit mAb

Dnmt3a Rabbit mAb (catalogue number 58848) is a recombinant rabbit-derived primary antibody validated for WB IHC ICC/IF FC, reactive with Human Mouse Rat samples. It targets DNA (cytosine-5)-methyltransferase 3A (DNMT3A): Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Applications
WB IHC ICC/IF FC
UniProt ID
Q9Y6K1
Gene
DNMT3A
Target organism
Homo sapiens
Catalogue number
58848
Brand
LABO Scientific
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

Target background

Target: DNA (cytosine-5)-methyltransferase 3A (DNMT3A) · Homo sapiens

Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18.

Subcellular location: Nucleus; Chromosome; Cytoplasm

Tissue specificity: Highly expressed in fetal tissues, skeletal muscle, heart, peripheral blood mononuclear cells, kidney, and at lower levels in placenta, brain, liver, colon, spleen, small intestine and lung

Sequence length: 912 aa · 101858 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.