Loading...
Dnmt3b Rabbit mAb

58519

Dnmt3b Rabbit mAb

Dnmt3b Rabbit mAb (catalogue number 58519) is a recombinant rabbit-derived primary antibody validated for WB ICC/IF, reactive with Human Mouse Rat samples. It targets DNA (cytosine-5)-methyltransferase 3B (DNMT3B): Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Applications
WB ICC/IF
UniProt ID
Q9UBC3
Gene
DNMT3B
Target organism
Homo sapiens
Catalogue number
58519
Brand
LABO Scientific
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

Target background

Target: DNA (cytosine-5)-methyltransferase 3B (DNMT3B) · Homo sapiens

Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing.

Subcellular location: Nucleus

Tissue specificity: Ubiquitous; highly expressed in fetal liver, heart, kidney, placenta, and at lower levels in spleen, colon, brain, liver, small intestine, lung, peripheral blood mononuclear cells, and skeletal muscle.

Sequence length: 853 aa · 95751 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.