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ADAM10 Antibody

24044

ADAM10 Antibody

ADAM10 Antibody (catalogue number 24044) is a rabbit-derived primary antibody validated for ELISA WB ICC, reactive with Human samples. It targets Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10): Transmembrane metalloprotease which mediates the ectodomain shedding of a myriad of transmembrane proteins, including adhesion proteins, growth factor precursors and cytokines being essential for development and tissue homeostasis. Supplied as 100ul at ₪2,157.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
ELISA WB ICC
UniProt ID
O14672
Gene
ADAM10
Target organism
Homo sapiens
Catalogue number
24044
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) · Homo sapiens

Transmembrane metalloprotease which mediates the ectodomain shedding of a myriad of transmembrane proteins, including adhesion proteins, growth factor precursors and cytokines being essential for development and tissue homeostasis. Associates with six members of the tetraspanin superfamily TspanC8 which regulate its exit from the endoplasmic reticulum and its substrate selectivity. Cleaves the membrane-bound precursor of TNF at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface.

Subcellular location: Cell membrane; Golgi apparatus membrane; Cytoplasmic vesicle, clathrin-coated vesicle; Cell projection, axon; Cell projection, dendrite; Cell junction, adherens junction; Cytoplasm

Tissue specificity: Expressed in the brain (at protein level). Expressed in spleen, lymph node, thymus, peripheral blood leukocyte, bone marrow, cartilage, chondrocytes and fetal liver

Sequence length: 748 aa · 84142 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.