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PTP1B (Phospho-Tyr66) Antibody

12630

PTP1B (Phospho-Tyr66) Antibody

PTP1B (Phospho-Tyr66) Antibody (catalogue number 12630) is a rabbit-derived primary antibody validated for Western blot, reactive with Hu Ms Rt samples. It targets Tyrosine-protein phosphatase non-receptor type 1 (PTPN1): Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms Rt
Applications
Western blot
UniProt ID
P18031
Gene
PTPN1
Target organism
Homo sapiens
Catalogue number
12630
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Tyrosine-protein phosphatase non-receptor type 1 (PTPN1) · Homo sapiens

Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET

Subcellular location: Endoplasmic reticulum membrane

Tissue specificity: Expressed in keratinocytes (at protein level)

Sequence length: 435 aa · 49967 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.