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Chemical structure of PTP1B-IN-9

GC61221

PTP1B-IN-9

Also known as (3E,5E)-3,5-bis[(3,4-dichlorophenyl)methylidene]piperidin-4-one

PTP1B-IN-9 is a ubiquitin-proteasome system (UPS)-stressor· PTP1B-IN-9 inhibits ubiquitin-mediated protein degradation upstream of the 20S proteasomal catalytic activites· PTP1B-IN-9 triggers a ubiquitin-proteasome-system (UPS)-stress response without affecting 20S proteasome catalytic activities· Anticancer activity

ChemicalCAS145888-79-5MW413.12FormulaC19H13Cl4NO
CAS number
145888-79-5
Molecular weight
413.12
Formula
C19H13Cl4NO
Solubility
DMSO： 5 mg/mL (12·10 mM)
InChIKey
GJPXGFGIFQWUOC-ACFHMISVSA-N
Catalogue number
GC61221
Brand
GLPBIO
Computed properties PubChem CID 5388806 · XLogP 5.7 · TPSA 29.1 Ų · H-bond donors 1
XLogP
5.7
TPSA
29.1 Ų
H-bond donors
1
H-bond acceptors
2
Rotatable bonds
2
Heavy atoms
25

SMILES C\1NC/C(=C\C2=CC(=C(C=C2)Cl)Cl)/C(=O)/C1=C/C3=CC(=C(C=C3)Cl)Cl

Computed descriptors from PubChem (CID 5388806), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.