HW209
Acetyl P53(K382) Mouse Monoclonal Antibody(1G7)
Acetyl P53(K382) Mouse Monoclonal Antibody(1G7) (catalogue number HW209) is a mouse-derived primary antibody validated for Immunohistochemistry, reactive with Hu Ms Rt samples. It targets Cellular tumor antigen p53 (TP53): Multifunctional transcription factor that induces cell cycle arrest, DNA repair or apoptosis upon binding to its target DNA sequence. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Mouse
- Reactivity
- Hu Ms Rt
- Applications
- Immunohistochemistry
- UniProt ID
- P04637
- Gene
- TP53
- Target organism
- Homo sapiens
- Catalogue number
- HW209
- Brand
- LABO Scientific
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Target background
Target: Cellular tumor antigen p53 (TP53) · Homo sapiens
Multifunctional transcription factor that induces cell cycle arrest, DNA repair or apoptosis upon binding to its target DNA sequence. Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Negatively regulates cell division by controlling expression of a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
Subcellular location: Cytoplasm; Nucleus; Nucleus, PML body; Endoplasmic reticulum; Mitochondrion matrix; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Tissue specificity: Ubiquitous. Isoforms are expressed in a wide range of normal tissues but in a tissue-dependent manner. Isoform 2 is expressed in most normal tissues but is not detected in brain, lung, prostate, muscle, fetal brain, spinal cord and fetal liver.
Sequence length: 393 aa · 43653 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il