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Chemical structure of (R)-AS-1

GC91906

(R)-AS-1

Also known as (2R)-N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide

(R)-AS-1 is a positive allosteric modulator of excitatory amino acid transporter 2 (EAAT2; EC50 = 11 nM in a glutamate uptake assay)

ChemicalCAS2506367-95-7MW260.3FormulaC14H16N2O3
CAS number
2506367-95-7
Molecular weight
260.3
Formula
C14H16N2O3
Solubility
Acetonitrile： Slightly soluble： 0·1–1 mg/ml,DMSO： Sparingly soluble： 1–10 mg/ml
InChIKey
XVSYJYYNUSOPAQ-SNVBAGLBSA-N
Catalogue number
GC91906
Brand
GLPBIO
Computed properties PubChem CID 155213164 · XLogP 0.4 · TPSA 66.5 Ų · H-bond donors 1
XLogP
0.4
TPSA
66.5 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
4
Heavy atoms
19

SMILES C[C@H](C(=O)NCC1=CC=CC=C1)N2C(=O)CCC2=O

Computed descriptors from PubChem (CID 155213164), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.