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Chemical structure of Bayer 18

GC91506

Bayer 18

Also known as 1-tert-butyl-3-[3-[[5-fluoro-4-[(1-hydroxy-2-methylpropan-2-yl)amino]pyrimidin-2-yl]amino]phenyl]urea

Bayer 18 is a tyrosine kinase 2 (TYK2) inhibitor (IC50 = 18·7 nM)

ChemicalCAS1251752-12-1MW390.5FormulaC19H27FN6O2
CAS number
1251752-12-1
Molecular weight
390.5
Formula
C19H27FN6O2
Solubility
DMSO: Sparingly Soluble: 1–10 mg/ml,Ethanol: Sparingly Soluble: 1–10 mg/ml
InChIKey
DYNMZYFOSRSMAC-UHFFFAOYSA-N
Catalogue number
GC91506
Brand
GLPBIO
Computed properties PubChem CID 73265273 · XLogP 2.4 · TPSA 111 Ų · H-bond donors 5
XLogP
2.4
TPSA
111 Ų
H-bond donors
5
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
28

SMILES CC(C)(C)NC(=O)NC1=CC=CC(=C1)NC2=NC=C(C(=N2)NC(C)(C)CO)F

Computed descriptors from PubChem (CID 73265273), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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