
GC76973
11β-HSD1-IN-8
Also known as methyl 3-oxo-3-[6-(trifluoromethyl)-3-pyridinyl]propanoate
11β-HSD1-IN-8 (compound c6a) is a 11β?HSD1 inhibitor with an IC50 value of 2·3 μM for human 11β?HSD1· 11β-HSD1-IN-8 can be used for the research of diabetes and cognitive decline
ChemicalCAS386704-15-0MW247.17FormulaC10H8F3NO3
- CAS number
- 386704-15-0
- Molecular weight
- 247.17
- Formula
- C10H8F3NO3
- Solubility
- DMSO: 100 mg/mL (404·58 mM; Need ultrasonic)
- InChIKey
- YXRIRKKHNGRGRZ-UHFFFAOYSA-N
- Catalogue number
- GC76973
- Brand
- GLPBIO
Computed properties PubChem CID 2775648 · XLogP 1.5 · TPSA 56.3 Ų · H-bond donors 0
- XLogP
- 1.5
- TPSA
- 56.3 Ų
- H-bond donors
- 0
- H-bond acceptors
- 7
- Rotatable bonds
- 4
- Heavy atoms
- 17
SMILES COC(=O)CC(=O)C1=CN=C(C=C1)C(F)(F)F
Computed descriptors from PubChem (CID 2775648), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il