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Chemical structure of 11β-HSD1-IN-8

GC76973

11β-HSD1-IN-8

Also known as methyl 3-oxo-3-[6-(trifluoromethyl)-3-pyridinyl]propanoate

11β-HSD1-IN-8 (compound c6a) is a 11β?HSD1 inhibitor with an IC50 value of 2·3 μM for human 11β?HSD1· 11β-HSD1-IN-8 can be used for the research of diabetes and cognitive decline

ChemicalCAS386704-15-0MW247.17FormulaC10H8F3NO3
CAS number
386704-15-0
Molecular weight
247.17
Formula
C10H8F3NO3
Solubility
DMSO: 100 mg/mL (404·58 mM; Need ultrasonic)
InChIKey
YXRIRKKHNGRGRZ-UHFFFAOYSA-N
Catalogue number
GC76973
Brand
GLPBIO
Computed properties PubChem CID 2775648 · XLogP 1.5 · TPSA 56.3 Ų · H-bond donors 0
XLogP
1.5
TPSA
56.3 Ų
H-bond donors
0
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
17

SMILES COC(=O)CC(=O)C1=CN=C(C=C1)C(F)(F)F

Computed descriptors from PubChem (CID 2775648), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.