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Chemical structure of BMS-986260

GC76952

BMS-986260

Also known as 6-[5-(3-chloro-4-fluorophenyl)-3-(2-hydroxyethyl)imidazol-4-yl]imidazo[1,2-b]pyridazine-3-carbonitrile

BMS-986260, an immuno-oncology agent, is a potent, selective, and orally active TGFβR1 inhibitor (IC50=1·6 nM)

ChemicalCAS2001559-19-7MW382.78FormulaC18H12ClFN6O
CAS number
2001559-19-7
Molecular weight
382.78
Formula
C18H12ClFN6O
Solubility
DMSO: 125 mg/mL (326·56 mM; Need ultrasonic)
InChIKey
VZZBCNXVZFAIQX-UHFFFAOYSA-N
Catalogue number
GC76952
Brand
GLPBIO
Computed properties PubChem CID 122510453 · XLogP 1.8 · TPSA 92 Ų · H-bond donors 1
XLogP
1.8
TPSA
92 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
27

SMILES C1=CC(=C(C=C1C2=C(N(C=N2)CCO)C3=NN4C(=NC=C4C#N)C=C3)Cl)F

Computed descriptors from PubChem (CID 122510453), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.