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Chemical structure of Argifin

GC76528

Argifin

Also known as (2R,5S,8S,11S,15S)-5-[3-[[amino-(methylcarbamoylamino)methylidene]amino]propyl]-8-benzyl-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentazacycloheptadecane-11,15-dicarboxylic acid

Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0·025 μM, 6·4 μM , 1·1 μM and 4·5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively

ChemicalCAS243975-37-3MW675.69FormulaC29H41N9O10
CAS number
243975-37-3
Molecular weight
675.69
Formula
C29H41N9O10
Solubility
DMSO： 100 mg/mL (148·00 mM; Need ultrasonic)
InChIKey
UHBHXSDKGLPPGO-HTDHLNIYSA-N
Catalogue number
GC76528
Brand
GLPBIO
Computed properties PubChem CID 449124 · XLogP -1.9 · TPSA 291 Ų · H-bond donors 9
XLogP
-1.9
TPSA
291 Ų
H-bond donors
9
H-bond acceptors
11
Rotatable bonds
9
Heavy atoms
48

SMILES C[C@@H]1C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@@H](CC(=O)N[C@@H](CC(=O)N1)C(=O)O)C(=O)O)CC2=CC=CC=C2)C)CCCN=C(N)NC(=O)NC

Computed descriptors from PubChem (CID 449124), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.