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Chemical structure of N-Formyl-Met-Leu-Phe-Lys

GC76495

N-Formyl-Met-Leu-Phe-Lys

Also known as (2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]hexanoic acid

N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3·5 nM, 6·7 μM and 0·88 μM for FPR1, FPR2 and FPR2-D2817·32G, respectively

ChemicalCAS67247-11-4MW565.73FormulaC27H43N5O6S
CAS number
67247-11-4
Molecular weight
565.73
Formula
C27H43N5O6S
Solubility
DMSO： 22·22 mg/mL (39·28 mM; ultrasonic and adjust pH to 3 with 1M HCl)
InChIKey
OERILMBTPCSYNG-MLCQCVOFSA-N
Catalogue number
GC76495
Brand
GLPBIO
Computed properties PubChem CID 9894161 · XLogP -0.2 · TPSA 205 Ų · H-bond donors 6
XLogP
-0.2
TPSA
205 Ų
H-bond donors
6
H-bond acceptors
8
Rotatable bonds
19
Heavy atoms
39

SMILES CC(C)C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCCN)C(=O)O)NC(=O)[C@H](CCSC)NC=O

Computed descriptors from PubChem (CID 9894161), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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